Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria
Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [(18)F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT.
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2013-11, Vol.49 (88), p.10361-10363 |
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| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [(18)F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT. |
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| ISSN: | 1359-7345 1364-548X 1364-548X |
| DOI: | 10.1039/c3cc45802d |