Synthesis of highly functionalized macrocycles by tandem multicomponent reactions and intramolecular Sonogashira cross-coupling

An efficient chemoselective process for the synthesis of 14- and 15-membered triazole-containing macrocycle compounds has been developed through the combination of two multicomponent reactions and an intramolecular Sonogashira cross-coupling reaction.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic & biomolecular chemistry 2013-11, Vol.11 (41), p.7232-7238
Hauptverfasser:	Niu, Teng-fei, Sun, Mu, Lv, Mei-fang, Yi, Wen-bin, Cai, Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Macrocyclic Compounds - chemical synthesis Macrocyclic Compounds - chemistry Molecular Structure Triazoles - chemical synthesis Triazoles - chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	An efficient chemoselective process for the synthesis of 14- and 15-membered triazole-containing macrocycle compounds has been developed through the combination of two multicomponent reactions and an intramolecular Sonogashira cross-coupling reaction.
ISSN:	1477-0520 1477-0539
DOI:	10.1039/c3ob41367e