Complementary prognostic utility of myocardial blush grade and ST-segment resolution after primary percutaneous coronary intervention: Analysis from the HORIZONS-AMI trial

Complementary prognostic utility of myocardial blush grade and ST-segment resolution after primary percutaneous coronary intervention: Analysis from the HORIZONS-AMI trial

Background Both ST-segment resolution (STR) and myocardial blush grade (MBG) have prognostic utility after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction. We sought to clarify how frequently MBG and STR provide discordant measures of reperfusion success and t...

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Veröffentlicht in:The American heart journal 2013-10, Vol.166 (4), p.676-683
Hauptverfasser: Brener, Sorin J., MD, Dizon, Jose M., MD, Mehran, Roxana, MD, Guerchicoff, Alejandra, PhD, Lansky, Alexandra J., MD, Farkouh, Michael, MD, Brodie, Bruce, MD, Guagliumi, Giulio, MD, Witzenbichler, Bernhard, MD, Fahy, Martin, MS, Parise, Helen, ScD, Stone, Gregg W., MD
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Cardiovascular
Coronary Angiography
Coronary Circulation - physiology
Electrocardiography
Female
Follow-Up Studies
Heart attacks
Humans
Laboratories
Male
Middle Aged
Mortality
Myocardial Infarction - diagnosis
Myocardial Infarction - physiopathology
Myocardial Infarction - surgery
Postoperative Period
Prognosis
Recovery of Function
Time Factors
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Zusammenfassung:Background Both ST-segment resolution (STR) and myocardial blush grade (MBG) have prognostic utility after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction. We sought to clarify how frequently MBG and STR provide discordant measures of reperfusion success and to determine the independent prognostic significance of each on long-term outcomes. Methods In HORIZONS-AMI, core laboratory measures of both MBG and STR were assessed in 2,367 patients undergoing primary PCI. Four groups were identified based on MBG (grades 2/3 vs 0/1) and STR (≥50% vs
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2013.07.025