Comparative analysis of viral genomes from acute and chronic hepatitis B reveals novel variants associated with a lower rate of chronicity

Infection with the hepatitis B virus (HBV) may lead to an acute or chronic infection. It is generally accepted that the clinical outcome of infection depends on the balance between host immunity and viral survival strategies. In order to persist, the virus needs to have a high rate of replication an...

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Veröffentlicht in:Journal of medical virology 2013-03, Vol.85 (3), p.419-424
Hauptverfasser: Chook, Jack Bee, Ngeow, Yun Fong, Khang, Tsung Fei, Ng, Kee Peng, Tiang, Yee Peng, Mohamed, Rosmawati
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Sprache:eng
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