Vitamin D is not associated with serologic response to influenza vaccine in adults over 50 years old

Highlights ► Community-dwelling adults aged 50 years old and older received influenza vaccine. ► We compared pre- and post-vaccination HAI titers and vitamin D. ► BMI and gender were significantly related to seroconversion to vaccine strains. ► Vitamin D is not related to response to influenza vacci...

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Veröffentlicht in:	Vaccine 2013-04, Vol.31 (16), p.2057-2061
Hauptverfasser:	Sundaram, Maria E, Talbot, H. Keipp, Zhu, Yuwei, Griffin, Marie R, Spencer, Sarah, Shay, David K, Coleman, Laura A
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Allergy and Immunology Antibodies, Viral - blood Antibodies, Viral - immunology Applied microbiology Biological and medical sciences blood serum Body Mass Index cohort studies elderly Female Fundamental and applied biological sciences. Psychology hemagglutination Hemagglutination Inhibition Tests Hemagglutinin Glycoproteins, Influenza Virus - immunology Humans Immunity, Cellular - immunology Influenza Influenza A Virus, H1N1 Subtype - immunology Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Influenza, Human - virology Laboratories Male Microbiology Middle Aged Older people prospective studies risk Seasons seroconversion Vaccination Vaccine Vaccine response Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vitamin D Vitamin D - blood vitamin D deficiency Vitamin D Deficiency - immunology volunteers
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Beschreibung
Zusammenfassung:	Highlights ► Community-dwelling adults aged 50 years old and older received influenza vaccine. ► We compared pre- and post-vaccination HAI titers and vitamin D. ► BMI and gender were significantly related to seroconversion to vaccine strains. ► Vitamin D is not related to response to influenza vaccine in older adults.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2013.02.028