Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli

A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as...

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Veröffentlicht in:Biotechnology letters 1986-08, Vol.8 (8), p.561-564
Hauptverfasser: PATERSON, S. L, FANE, A. G, FELL, C. J. D, ROGERS, P. L. R
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container_title Biotechnology letters
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creator PATERSON, S. L
FANE, A. G
FELL, C. J. D
ROGERS, P. L. R
description A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation.
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ispartof Biotechnology letters, 1986-08, Vol.8 (8), p.561-564
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source Springer Nature - Complete Springer Journals
subjects Biological and medical sciences
bioreactors
Biotechnology
Escherichia coli
fatty acids
Fundamental and applied biological sciences. Psychology
immobilized cells
Methods. Procedures. Technologies
Microbial engineering. Fermentation and microbial culture technology
oxygen
phenylalanine
title Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli
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