Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli
A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as...
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Veröffentlicht in: | Biotechnology letters 1986-08, Vol.8 (8), p.561-564 |
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container_title | Biotechnology letters |
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creator | PATERSON, S. L FANE, A. G FELL, C. J. D ROGERS, P. L. R |
description | A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation. |
doi_str_mv | 10.1007/BF01028083 |
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L ; FANE, A. G ; FELL, C. J. D ; ROGERS, P. L. R</creator><creatorcontrib>PATERSON, S. L ; FANE, A. G ; FELL, C. J. D ; ROGERS, P. L. R</creatorcontrib><description>A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation.</description><identifier>ISSN: 0141-5492</identifier><identifier>EISSN: 1573-6776</identifier><identifier>DOI: 10.1007/BF01028083</identifier><identifier>CODEN: BILED3</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Biological and medical sciences ; bioreactors ; Biotechnology ; Escherichia coli ; fatty acids ; Fundamental and applied biological sciences. Psychology ; immobilized cells ; Methods. Procedures. Technologies ; Microbial engineering. 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D</creatorcontrib><creatorcontrib>ROGERS, P. L. R</creatorcontrib><title>Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli</title><title>Biotechnology letters</title><description>A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation.</description><subject>Biological and medical sciences</subject><subject>bioreactors</subject><subject>Biotechnology</subject><subject>Escherichia coli</subject><subject>fatty acids</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>immobilized cells</subject><subject>Methods. Procedures. Technologies</subject><subject>Microbial engineering. 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Procedures. Technologies</topic><topic>Microbial engineering. Fermentation and microbial culture technology</topic><topic>oxygen</topic><topic>phenylalanine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PATERSON, S. L</creatorcontrib><creatorcontrib>FANE, A. G</creatorcontrib><creatorcontrib>FELL, C. J. D</creatorcontrib><creatorcontrib>ROGERS, P. L. 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subjects | Biological and medical sciences bioreactors Biotechnology Escherichia coli fatty acids Fundamental and applied biological sciences. Psychology immobilized cells Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology oxygen phenylalanine |
title | Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli |
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