Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli

A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as...

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Veröffentlicht in:	Biotechnology letters 1986-08, Vol.8 (8), p.561-564
Hauptverfasser:	PATERSON, S. L, FANE, A. G, FELL, C. J. D, ROGERS, P. L. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences bioreactors Biotechnology Escherichia coli fatty acids Fundamental and applied biological sciences. Psychology immobilized cells Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology oxygen phenylalanine
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Zusammenfassung:	A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant of E. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation.
ISSN:	0141-5492 1573-6776
DOI:	10.1007/BF01028083