Insulin antibodies in patients receiving penicillamine
In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia. When 30 additional patients receiving penicillamine were screened, another patient was discovered to have antibodies to insulin. The level of antib...
Gespeichert in:
| Veröffentlicht in: | The American journal of medicine 1985-01, Vol.78 (5), p.857-860 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 860 |
|---|---|
| container_issue | 5 |
| container_start_page | 857 |
| container_title | The American journal of medicine |
| container_volume | 78 |
| creator | Benson, Edward A. Healey, L.A. Barron, Edward J. |
| description | In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia. When 30 additional patients receiving penicillamine were screened, another patient was discovered to have antibodies to insulin. The level of antibody fell sharply in both patients after penicillamine was discontinued. This particular immunologic reaction to penicillamine has not been reported previously. |
| doi_str_mv | 10.1016/0002-9343(85)90294-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_14397337</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0002934385902943</els_id><sourcerecordid>14397337</sourcerecordid><originalsourceid>FETCH-LOGICAL-c417t-76b7e047f5ee90e20d1c72a2ed0fa96d2b5f840126e4f252155ffb49420f32ce3</originalsourceid><addsrcrecordid>eNp9kE1LxDAQhoMouq7-A4UeRPRQzXebiyCLHwsLXvQc0nQikTatTXfBf2_WLXv0NAzzvMPLg9AFwXcEE3mPMaa5YpzdlOJWYap4zg7QjAgh8oJIeohme-QEncb4lVashDxGx0wpJiWfIbkMcd34kJkw-qqrPcQsbb0ZPYQxZgNY8BsfPrMegre-aUzrA5yhI2eaCOfTnKOP56f3xWu-entZLh5XueWkGPNCVgVgXjgBoDBQXBNbUEOhxs4oWdNKuJJjQiVwRwVN3Z2ruOIUO0YtsDm63v3th-57DXHUrY8WUosA3TpqwpkqGCsSyHegHboYB3C6H3xrhh9NsN7q0lsXeutCl0L_6dIsxS6n_-uqhXofmvyk-9V0N9Gaxg0mWB_3WCkSRVXCHnYYJBcbD4OONvmzUPskcNR15__v8QsuuoV6</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14397337</pqid></control><display><type>article</type><title>Insulin antibodies in patients receiving penicillamine</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Benson, Edward A. ; Healey, L.A. ; Barron, Edward J.</creator><creatorcontrib>Benson, Edward A. ; Healey, L.A. ; Barron, Edward J.</creatorcontrib><description>In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia. When 30 additional patients receiving penicillamine were screened, another patient was discovered to have antibodies to insulin. The level of antibody fell sharply in both patients after penicillamine was discontinued. This particular immunologic reaction to penicillamine has not been reported previously.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/0002-9343(85)90294-3</identifier><identifier>PMID: 3993664</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; antirheumatic agents ; Arthritis, Rheumatoid - drug therapy ; Arthritis, Rheumatoid - immunology ; autoantibodies ; Autoantibodies - biosynthesis ; Biological and medical sciences ; Female ; Hormones. Endocrine system ; Humans ; hypoglycemia ; Hypoglycemia - etiology ; insulin ; Insulin Antibodies - biosynthesis ; Male ; Medical sciences ; Middle Aged ; penicillamine ; Penicillamine - adverse effects ; Pharmacology. Drug treatments ; side effects</subject><ispartof>The American journal of medicine, 1985-01, Vol.78 (5), p.857-860</ispartof><rights>1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-76b7e047f5ee90e20d1c72a2ed0fa96d2b5f840126e4f252155ffb49420f32ce3</citedby><cites>FETCH-LOGICAL-c417t-76b7e047f5ee90e20d1c72a2ed0fa96d2b5f840126e4f252155ffb49420f32ce3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9343(85)90294-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8536629$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3993664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Benson, Edward A.</creatorcontrib><creatorcontrib>Healey, L.A.</creatorcontrib><creatorcontrib>Barron, Edward J.</creatorcontrib><title>Insulin antibodies in patients receiving penicillamine</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia. When 30 additional patients receiving penicillamine were screened, another patient was discovered to have antibodies to insulin. The level of antibody fell sharply in both patients after penicillamine was discontinued. This particular immunologic reaction to penicillamine has not been reported previously.</description><subject>Adult</subject><subject>antirheumatic agents</subject><subject>Arthritis, Rheumatoid - drug therapy</subject><subject>Arthritis, Rheumatoid - immunology</subject><subject>autoantibodies</subject><subject>Autoantibodies - biosynthesis</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Hormones. Endocrine system</subject><subject>Humans</subject><subject>hypoglycemia</subject><subject>Hypoglycemia - etiology</subject><subject>insulin</subject><subject>Insulin Antibodies - biosynthesis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>penicillamine</subject><subject>Penicillamine - adverse effects</subject><subject>Pharmacology. Drug treatments</subject><subject>side effects</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMouq7-A4UeRPRQzXebiyCLHwsLXvQc0nQikTatTXfBf2_WLXv0NAzzvMPLg9AFwXcEE3mPMaa5YpzdlOJWYap4zg7QjAgh8oJIeohme-QEncb4lVashDxGx0wpJiWfIbkMcd34kJkw-qqrPcQsbb0ZPYQxZgNY8BsfPrMegre-aUzrA5yhI2eaCOfTnKOP56f3xWu-entZLh5XueWkGPNCVgVgXjgBoDBQXBNbUEOhxs4oWdNKuJJjQiVwRwVN3Z2ruOIUO0YtsDm63v3th-57DXHUrY8WUosA3TpqwpkqGCsSyHegHboYB3C6H3xrhh9NsN7q0lsXeutCl0L_6dIsxS6n_-uqhXofmvyk-9V0N9Gaxg0mWB_3WCkSRVXCHnYYJBcbD4OONvmzUPskcNR15__v8QsuuoV6</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Benson, Edward A.</creator><creator>Healey, L.A.</creator><creator>Barron, Edward J.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SQ</scope><scope>7T5</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope></search><sort><creationdate>19850101</creationdate><title>Insulin antibodies in patients receiving penicillamine</title><author>Benson, Edward A. ; Healey, L.A. ; Barron, Edward J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-76b7e047f5ee90e20d1c72a2ed0fa96d2b5f840126e4f252155ffb49420f32ce3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>antirheumatic agents</topic><topic>Arthritis, Rheumatoid - drug therapy</topic><topic>Arthritis, Rheumatoid - immunology</topic><topic>autoantibodies</topic><topic>Autoantibodies - biosynthesis</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Hormones. Endocrine system</topic><topic>Humans</topic><topic>hypoglycemia</topic><topic>Hypoglycemia - etiology</topic><topic>insulin</topic><topic>Insulin Antibodies - biosynthesis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>penicillamine</topic><topic>Penicillamine - adverse effects</topic><topic>Pharmacology. Drug treatments</topic><topic>side effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Benson, Edward A.</creatorcontrib><creatorcontrib>Healey, L.A.</creatorcontrib><creatorcontrib>Barron, Edward J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Endocrinology Abstracts</collection><collection>Immunology Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Benson, Edward A.</au><au>Healey, L.A.</au><au>Barron, Edward J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Insulin antibodies in patients receiving penicillamine</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>78</volume><issue>5</issue><spage>857</spage><epage>860</epage><pages>857-860</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract>In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia. When 30 additional patients receiving penicillamine were screened, another patient was discovered to have antibodies to insulin. The level of antibody fell sharply in both patients after penicillamine was discontinued. This particular immunologic reaction to penicillamine has not been reported previously.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3993664</pmid><doi>10.1016/0002-9343(85)90294-3</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9343 |
| ispartof | The American journal of medicine, 1985-01, Vol.78 (5), p.857-860 |
| issn | 0002-9343 1555-7162 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_14397337 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult antirheumatic agents Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - immunology autoantibodies Autoantibodies - biosynthesis Biological and medical sciences Female Hormones. Endocrine system Humans hypoglycemia Hypoglycemia - etiology insulin Insulin Antibodies - biosynthesis Male Medical sciences Middle Aged penicillamine Penicillamine - adverse effects Pharmacology. Drug treatments side effects |
| title | Insulin antibodies in patients receiving penicillamine |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T11%3A18%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Insulin%20antibodies%20in%20patients%20receiving%20penicillamine&rft.jtitle=The%20American%20journal%20of%20medicine&rft.au=Benson,%20Edward%20A.&rft.date=1985-01-01&rft.volume=78&rft.issue=5&rft.spage=857&rft.epage=860&rft.pages=857-860&rft.issn=0002-9343&rft.eissn=1555-7162&rft.coden=AJMEAZ&rft_id=info:doi/10.1016/0002-9343(85)90294-3&rft_dat=%3Cproquest_cross%3E14397337%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14397337&rft_id=info:pmid/3993664&rft_els_id=0002934385902943&rfr_iscdi=true |