Horizontal gene transfer of a genetic island encoding a type III secretion system distributed in Vibrio cholerae

ABSTRACT Twelve Vibrio cholerae isolates with genes for a type III secretion system (T3SS) were detected among 110 environmental and 14 clinical isolates. T3SS‐related genes were distributed among the various serogroups and pulsed‐field gel electrophoresis of NotI‐digested genomes showed genetic div...

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Veröffentlicht in:	Microbiology and immunology 2013-05, Vol.57 (5), p.334-339
Hauptverfasser:	Morita, Masatomo, Yamamoto, Shouji, Hiyoshi, Hirotaka, Kodama, Toshio, Okura, Masatoshi, Arakawa, Eiji, Alam, Munirul, Ohnishi, Makoto, Izumiya, Hidemasa, Watanabe, Haruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Cholera Cholera - microbiology Chromosomes, Bacterial Electrophoresis, Gel, Pulsed-Field Environmental Microbiology Gene Transfer, Horizontal Genes Genetic Variation Genomic Islands Genotype horizontal gene transfer Humans Membrane Transport Proteins - genetics Microbiology Molecular Typing Multigene Family natural transformation Polymorphism, Restriction Fragment Length Vibrio cholerae Vibrio cholerae - classification Vibrio cholerae - genetics Vibrio cholerae - isolation & purification Vibrio cholerae - pathogenicity Virulence Factors - genetics
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Zusammenfassung:	ABSTRACT Twelve Vibrio cholerae isolates with genes for a type III secretion system (T3SS) were detected among 110 environmental and 14 clinical isolates. T3SS‐related genes were distributed among the various serogroups and pulsed‐field gel electrophoresis of NotI‐digested genomes showed genetic diversity in these strains. However, the restriction fragment length polymorphism profiles of the T3SS‐related genes had similar patterns. Additionally, naturally competent T3SS‐negative V. cholerae incorporated the ca. 47 kb gene cluster of T3SS, which had been integrated into a site on the chromosome by recombination. Therefore, it is suggested that horizontal gene transfer of T3SS‐related genes occurs among V. cholerae in natural ecosystems.
ISSN:	0385-5600 1348-0421
DOI:	10.1111/1348-0421.12039