Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy

Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-07, Vol.48 (53), p.6627-6629
Hauptverfasser: Redshaw, Carl, Elsegood, Mark R J, Frese, Josef W A, Ashby, Shane, Chao, Yimin, Mueller, Anja
Format: Artikel
Sprache:eng
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Zusammenfassung:Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc32060f