Analytical characterization and antimicrobial properties of novel copper nanoparticle–loaded electrosynthesized hydrogel coatings

In this study, a novel antimicrobial coating was developed to avoid infections and to provide sterile conditions for stainless steel devices. Poly(ethylene glycol diacrylate) hydrogel thin films were modified with copper-based nanoparticles, following two different entrapment procedures. These coatings were firmly attached on metal substrates by means of a simple and fast electrochemical polymerization technique. The surface composition of the Cu nanoparticles–modified hydrogel coatings and their bactericidal effect against Staphylococcus aureus and Escherichia coli was studied, and the efficacy of such systems in preventing bacterial infections demonstrated.