Adipose stem cell therapy for soft tissue reconstruction

Undifferentiated adipose stromal cell populations were noted to have multi-lineage potential and qualities similar to bone marrow mesenchymal stem cells.7 Their ability to differentiate into adipocytes,8 release growth factors,9 and integrate structurally into new blood vessels during angiogenesis,1...

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Veröffentlicht in:The Lancet (British edition) 2013-09, Vol.382 (9898), p.1077-1079
Hauptverfasser: Rubin, J Peter, Marra, Kacey G
Format: Artikel
Sprache:eng
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Zusammenfassung:Undifferentiated adipose stromal cell populations were noted to have multi-lineage potential and qualities similar to bone marrow mesenchymal stem cells.7 Their ability to differentiate into adipocytes,8 release growth factors,9 and integrate structurally into new blood vessels during angiogenesis,10 make these cells therapeutically attractive. A significant disadvantage is that a large amount of fat is needed to obtain cells. [...]patients with little body fat might not be candidates for the procedure.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(13)61744-4