Production of porous Ni-Ti alloy and test of its biocompatibility under in-vivo conditions

Biomaterials have been out of commonly used materials in biomedical applications in recent years. Today among the mostly-used biocompatible metals are especially Ni-Ti alloys. For conducting this study, having extensive usage area in biomedical applications, Ni and Ti materials were utilized for an alloy production. Following being mixed using a suitable mixer at 49Ni/51Ti %wt., the alloy was exposed to cold pressure of 200 MPa and sintered in a mold. In addition, the material gained porosity appearance thanks to usage of the synthesized (SHS) method and then the final shape of the specimen was taken using the method of wire electro erosion discharge machining (WEDM). Afterwards, the specimen was subjected to the biocompatibility test in in-vivo environment by means of on a 3-year-old female dog.