Cardiac Pacing and Central Hemodynamics in Experimental Propoxyphene Induced Shock

Cardiac Pacing and Central Hemodynamics in Experimental Propoxyphene Induced Shock

Abstract Coronary sinus pacing was evaluated in 10 pigs with propoxyphene induced cardiac failure. During the early phase of intoxication cardiac pacing improved cardiac function slightly but significantly worsened it in severely intoxicated animals. The results are consistent with marked negative i...

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Veröffentlicht in:Clinical toxicology (Philadelphia, Pa.) Pa.), 1985, Vol.23 (4-6), p.353-356
Hauptverfasser: Strøm, J., Häggmark, S., Madsen, P. S., Reiz, S., Bredgaard Sørensen, M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cardiac Pacing, Artificial
Dextropropoxyphene - poisoning
Hemodynamics - drug effects
Shock - chemically induced
Shock - physiopathology
Shock - therapy
Swine
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Zusammenfassung:Abstract Coronary sinus pacing was evaluated in 10 pigs with propoxyphene induced cardiac failure. During the early phase of intoxication cardiac pacing improved cardiac function slightly but significantly worsened it in severely intoxicated animals. The results are consistent with marked negative inotropic action of propoxyphene in overdose.
ISSN:1556-3650
0731-3810
1556-9519
DOI:10.3109/15563658508990644