Prevalence of rubella IgG antibodies among pregnant women in Zaria, Nigeria

Abstract Rubella is a vaccine-preventable viral infection which in pregnancy can lead to foetal wastage and congenital malformations. A rubella IgG serosurvey of 430 consenting pregnant women attending the antenatal clinic was conducted at the Ahmadu Bello University Teaching Hospital, Zaria between...

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Veröffentlicht in:International health 2010-06, Vol.2 (2), p.156-159
Hauptverfasser: Amina, Mohammed-Durosinlorun, Oladapo, Shittu, Habib, Sadauki, Adebola, Olayinka, Bimbo, Kolawole, Daniel, Adejo
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Sprache:eng
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Zusammenfassung:Abstract Rubella is a vaccine-preventable viral infection which in pregnancy can lead to foetal wastage and congenital malformations. A rubella IgG serosurvey of 430 consenting pregnant women attending the antenatal clinic was conducted at the Ahmadu Bello University Teaching Hospital, Zaria between 1 May 2007 and 29 February 2008. Questionnaires were also used to assess their level of awareness and pregnancy outcomes noted. Of the 430 serum samples tested, 421 (97.9%) were positive and 9 (2.1%) were negative for rubella IgG antibody. Differences in sociodemographic factors were of little significance between the groups and awareness of the infection was low. This high prevalence suggests that a sustained viral circulation exists in children and infection occurs early in infancy hence a high level of immunity exists in pregnant women with low levels of complications. In the absence of mass vaccination, all seronegative women should be vaccinated after delivery.
ISSN:1876-3413
1876-3405
DOI:10.1016/j.inhe.2010.03.004