Volatile nitrosamines in the main stream smoke of black tobacco

Volatile nitrosamines in the main stream smoke of black tobacco

The cigarettes studied are smoked through an automatic device. The mainstream smoke is trapped in Citrate-Phosphate buffer pH 4.5 containing 20 mM ascorbic acid. The volatile nitrosamines are extracted in dichloromethane, purified on alumina column, then analysed by gas-chromatography with a thermal...

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Veröffentlicht in:Journal of cancer research and clinical oncology 1984-01, Vol.108 (1), p.157-159
Hauptverfasser: TRUHAUT, R, NGUYEN PHY LICH, CASTEGNARO, M, BOURGADE, M. C, MARTIN, C
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Medical sciences
Nicotiana - analysis
Nitrosamines - analysis
Plants, Toxic
Smoke - analysis
Tobacco, tobacco smoking
Toxicology
Volatilization
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Zusammenfassung:The cigarettes studied are smoked through an automatic device. The mainstream smoke is trapped in Citrate-Phosphate buffer pH 4.5 containing 20 mM ascorbic acid. The volatile nitrosamines are extracted in dichloromethane, purified on alumina column, then analysed by gas-chromatography with a thermal energy analyzer (TEA) detector. The two main volatile nitrosamines quantified are: Nitrosodimethylamine and Nitrosopyrrolidine.
ISSN:0171-5216
1432-1335
DOI:10.1007/BF00390989