Prevalence and Antibiotic Susceptibility Patterns of Bloodstream Salmonella Infections in a Tertiary Care Hospital, Dhaka

This study was conducted to determine the status of bloodstream Salmonella infection and their antibiotic susceptibility patterns in a tertiary care hospital at Dhaka, Bangladesh. Six hundred and fifty six blood samples collected from clinically diagnosed enteric fever patients. Salmonella enterica serovar typhi and paratyphi isolates were identified by standard microbiological and biochemical procedures. Ninety four isolates of Salmonella typhi and 59 isolates of S. paratyphi were isolated. Results show young, neonates and elderly persons are more prone to Salmonella infection and males are more susceptible to Salmonella septicemia than females. Most of the isolates Salmonella spp. were Multi-drug Resistance and showed high resistance against Cefixime, ceftriaxone, cefipime, ciprofloxacin, chloramphenicol and meropenem. Nalidixic acid was found to be effective against them. Specific antibiotic utilization strategies like antibiotic restriction, combination therapy and usage according to the standard antimicrobial susceptibility testing may help to decrease or prevent the emergence of resistance and incidence of blood stream infections.