Synthesis of Pyridine-Based 1,3,4-Oxadiazole Derivative as Fluorescence Turn-On Sensor for High Selectivity of Ag

An oxadiazole derivative(OXD) containing symmetrical pyridine-2-formamidophenyl-binded moiety was synthesised as fluorescence turn-on sensor OA1 . Its ultraviolet–visible(UV–vis) and fluorescent spectra(FS) gave prominent fluorescence enhancement only for monovalent silver ion(Ag + ) in HEPES buffer solution (10 mM, pH = 7.0, DMF-H 2 O, 9:1, v/v), which indicated the photo-induced electron transfer(PET) occurred from the donor of pyridine-2-formamidophenyl group to oxadiazole fluorophore. The present study demonstrated that OA1 was a viable candidate as fluorescent receptor for a new Ag + sensor. And the results of fluorescent spectral titration showed this sensor formed 1:1 complex with Ag + .