Epileptic spasms in tuberous sclerosis complex

Epileptic spasms in tuberous sclerosis complex

Highlights • Epileptic spasms are not uncommon in older patients with tuberous sclerosis complex. • Epileptic spasms are difficult to treat, but vigabatrin proved effective for some. • Epilepsy surgery was also successful for some of our patients. • Further research is needed to understand this unde...

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Veröffentlicht in:Epilepsy research 2013-09, Vol.106 (1), p.200-210
Hauptverfasser: Hsieh, David T, Jennesson, Melanie M, Thiele, Elizabeth A
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age of Onset
Anticonvulsants - therapeutic use
Anticonvulsants. Antiepileptics. Antiparkinson agents
Autistic Disorder - complications
Biological and medical sciences
Child
Child, Preschool
Cognition - physiology
Data Collection
Electroencephalography
Epilepsy - drug therapy
Epilepsy - etiology
Epilepsy - genetics
Epileptic spasms
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Humans
Infant
Infantile spasms
Magnetic Resonance Imaging
Male
Medical sciences
Nervous system (semeiology, syndromes)
Neurology
Neuropharmacology
Neuropsychological Tests
Pharmacology. Drug treatments
Prognosis
Retrospective Studies
Spasm - drug therapy
Spasm - etiology
Spasm - genetics
Spasms, Infantile - etiology
Treatment Outcome
Tuberous Sclerosis - complications
Tuberous Sclerosis - genetics
Tuberous sclerosis complex
Tumors of the nervous system. Phacomatoses
Vigabatrin
Young Adult
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Zusammenfassung:Highlights • Epileptic spasms are not uncommon in older patients with tuberous sclerosis complex. • Epileptic spasms are difficult to treat, but vigabatrin proved effective for some. • Epilepsy surgery was also successful for some of our patients. • Further research is needed to understand this under recognized entity.
ISSN:0920-1211
1872-6844
DOI:10.1016/j.eplepsyres.2013.05.003