Can we predict a favourable response to Ketogenic Diet Therapies for drug-resistant epilepsy?

Highlights • We searched for putative predictors of response to Ketogenic Diet Therapies (KDT) for epilepsy. • No specific factors appear to affect response to KDT in humans – evidence is inconsistent. • Gender and intellectual status do not seem to affect response to KDT. • More studies are needed...

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Veröffentlicht in:	Epilepsy research 2013-09, Vol.106 (1), p.1-16
Hauptverfasser:	Schoeler, Natasha E, Cross, J. Helen, Sander, Josemir W, Sisodiya, Sanjay M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - therapeutic use Biological and medical sciences Biomarkers Diet, Ketogenic Dietary treatments Drug Resistance Epilepsy - diet therapy Epilepsy - drug therapy Epilepsy - etiology Epilepsy - genetics Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Intelligence Male Medical sciences Nervous system (semeiology, syndromes) Neurology Outcomes Predictive Value of Tests Review Sex Characteristics Treatment Outcome
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Zusammenfassung:	Highlights • We searched for putative predictors of response to Ketogenic Diet Therapies (KDT) for epilepsy. • No specific factors appear to affect response to KDT in humans – evidence is inconsistent. • Gender and intellectual status do not seem to affect response to KDT. • More studies are needed to improve understanding of the mechanisms behind KDT.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2013.06.002