The physics of tobacco mosaic virus and virus-based devices in biotechnology

Highlights • Diffraction and cryo-EM provide a detailed picture of TMV in various states, even during assembly. • TMV is surprisingly resilient against many polar organic solvents, and against protonation. • A large range of macro- and nanoscale spectroscopic methods can be used to discover more phy...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2013-09, Vol.31 (9), p.530-538
Hauptverfasser:	Alonso, J.M, Górzny, M.Ł, Bittner, A.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Behavior Biological and medical sciences Biotechnology Biotechnology - trends Chemical properties Chemistry electromagnetic fields Environmental changes Fabrication Fundamental and applied biological sciences. Psychology Genetic Engineering - trends Genomes Humans Internal Medicine Lymphoma mammals Molecular Sequence Data nanoscale devices Nanotechnology - trends Physical properties physicochemical properties Physics surface adsorption Temperature themodynamics thermodynamics Tobacco mosaic virus Tobacco Mosaic Virus - chemistry Tobacco Mosaic Virus - physiology Vaccines Viruses
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Beschreibung
Zusammenfassung:	Highlights • Diffraction and cryo-EM provide a detailed picture of TMV in various states, even during assembly. • TMV is surprisingly resilient against many polar organic solvents, and against protonation. • A large range of macro- and nanoscale spectroscopic methods can be used to discover more physical properties. • Technological uses are mainly based on inorganic material on TMV, hence on inorganic tubes of >20 nm diameter.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2013.05.013