Association of 25-hydroxyvitamin D with type 2 diabetes among patients undergoing coronary angiography: cross-sectional findings from the LUdwigshafen Risk and Cardiovascular Health (LURIC) Study

Summary Objective Evidence suggests that vitamin D may protect against the onset of diabetes. However, the mechanisms underlying the role of vitamin D on glycaemic status are unclear and warrant further investigation. We sought to determine the relationship between serum 25‐hydroxyvitamin D (25[OH]D) and glycaemic status among intermediate‐to‐high‐risk patients scheduled for coronary angiography. Methods Participants were 3316 male and female patients (mean ± SD age, 62·7 ± 10·6 years). Four categories were formed according to serum 25[OH]D levels. The association between serum 25[OH]D and diabetes was assessed using multivariable logistic regression. Results Fasting and 2 h post‐load glucose, HbA1c and the HOMA‐IR indices diminished with increasing serum 25[OH]D levels (P