The Impact of Obesity as Determined by Modified Body Mass Index on Long-Term Outcome After Liver Transplantation: Canadian Single-Center Experience

Abstract Background Obesity is thought to be associated with higher rates of morbidity and mortality after liver transplantation (LT); however, its actual impact is difficult to evaluate, in part because of the confounding effects of fluid accumulation on body mass index (BMI). Objective We sought t...

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Veröffentlicht in:Transplantation proceedings 2013-07, Vol.45 (6), p.2288-2294
Hauptverfasser: Tanaka, T, Renner, E.L, Selzner, N, Therapondos, G, Lilly, L.B
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Sprache:eng
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Zusammenfassung:Abstract Background Obesity is thought to be associated with higher rates of morbidity and mortality after liver transplantation (LT); however, its actual impact is difficult to evaluate, in part because of the confounding effects of fluid accumulation on body mass index (BMI). Objective We sought to define the effects of conventional BMI (cBMI) and modified BMI (mBMI; calculated by multiplying the BMI by serum albumin level to compensate for fluid accumulation), on the outcome of LT recipients overall. Methods A cohort of 507 patients who underwent LT from April 2000 to August 2006 were analyzed. Results Pre-LT diabetes mellitus was seen somewhat more frequently in the higher mBMI group ( P = .054), whereas there was no difference across cBMI categories. The recipients at extremes of cBMI (>40 kg/m2 and
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2012.11.009