Functionalized polymeric liposomes. Efficient immobilization of alpha chymotrypsin

Functionalized polymeric liposomes. Efficient immobilization of alpha chymotrypsin

A polymerizable phospholipid has been synthesized having a latent aldehyde moiety in the head group. Photopolymerized vesicles which have been prepared from this phosphatidylcholine have been successfully conjugated to alpha chymotrypsin. A high degree of loading was achieved with significant retent...

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Veröffentlicht in:Biochemical and biophysical research communications 1984-01, Vol.119 (2), p.649-651
Hauptverfasser: Regen, S L, Singh, M, Samuel, NKP
Format: Artikel
Sprache:eng
Schlagworte:
alpha -chymotrypsin
immobilized enzymes
liposomes
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Zusammenfassung:A polymerizable phospholipid has been synthesized having a latent aldehyde moiety in the head group. Photopolymerized vesicles which have been prepared from this phosphatidylcholine have been successfully conjugated to alpha chymotrypsin. A high degree of loading was achieved with significant retention of enzymatic function.
ISSN:0006-291X