Experimental evaluation of the prophylactic and therapeutic effects of hydrocortisone in haemorrhagic shock
The prophylactic and therapeutic effects of hydrocortisone in severe haemorrhagic shock were evaluatd by metabolic, biochemical and haematological investigations in a rabbit model. Hydrocortisone therapy combined with volume replacement 1 hour after the haemorrhagic insult had several beneficial eff...
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Veröffentlicht in: | South African Medical Journal/Suid-Afrikaanse Mediese Tydskrift 1985-01, Vol.67 (16), p.637-642 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | The prophylactic and therapeutic effects of hydrocortisone in severe haemorrhagic shock were evaluatd by metabolic, biochemical and haematological investigations in a rabbit model. Hydrocortisone therapy combined with volume replacement 1 hour after the haemorrhagic insult had several beneficial effects. The metabolic capacity of liver and kidney tissues was improved, the lysosomal concentration remained within normal limits, and the mean blood pressure and pulse pressure were maintained better than in controls. |
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ISSN: | 0038-2469 |