The effect of a new 9-aminoacridine derivative on working and long-term memory in rats

The effect of a new 9-aminoacridine derivative on working and long-term memory in rats

The effects of Vp, a new 9-aminoacridine derivative, on the radial maze performance of intact and scopolamine-treated rats were compared with those of amiridin and tacrine. In intact rats Vp improved the formation of long-term spatial memory and has a positive effect on working memory at the initial...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1999-02, Vol.127 (2), p.183-185
Hauptverfasser: Burov, Yu. V., Borisova, A. O., Robakidze, T. N., Goncharenko, S. B.
Format: Artikel
Sprache:eng
Schlagworte:
Animal memory
Rodents
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Zusammenfassung:The effects of Vp, a new 9-aminoacridine derivative, on the radial maze performance of intact and scopolamine-treated rats were compared with those of amiridin and tacrine. In intact rats Vp improved the formation of long-term spatial memory and has a positive effect on working memory at the initial stage of training. In scopolamine-treated rats Vp reduced the amnesic effects of scopolamine on both kinds of memory.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433109