Recombinant human leptin attenuates stress axis activity in common carp ( Cyprinus carpio L.)

Recombinant human leptin attenuates stress axis activity in common carp ( Cyprinus carpio L.)

Highlights ► RhLeptin suppresses basal and CRF-induced ACTH secretion from carp pituitary glands. ► RhLeptin suppresses basal interrenal cortisol secretion in vitro . ► Leptin may be key in adaptation processes when energy partitioning is crucial.

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Bibliographische Detailangaben
Veröffentlicht in:General and comparative endocrinology 2012-08, Vol.178 (1), p.75-81
Hauptverfasser: Gorissen, Marnix, Bernier, Nicholas J, Manuel, Remy, de Gelder, Stefan, Metz, Juriaan R, Huising, Mark O, Flik, Gert
Format: Artikel
Sprache:eng
Schlagworte:
ACTH
Animals
Asialoglycoprotein Receptor - metabolism
Carps - metabolism
Cortisol
CRF
Cyprinus carpio
Endocrinology & Metabolism
evolution
fish
Freshwater
Humans
Kidney - drug effects
Kidney - metabolism
kidneys
Leptin
Leptin - pharmacology
netting
Pituitary Gland - drug effects
Pituitary Gland - metabolism
Recombinant Proteins - pharmacology
secretion
Stress axis
Stress, Physiological
Teleostean fish
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Zusammenfassung:Highlights ► RhLeptin suppresses basal and CRF-induced ACTH secretion from carp pituitary glands. ► RhLeptin suppresses basal interrenal cortisol secretion in vitro . ► Leptin may be key in adaptation processes when energy partitioning is crucial.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2012.04.004