Molecular connectivity of phenols and their toxicity to fish

The relation between the acute toxicity of phenolic compounds to fish (Pimephales promelas) and the chemical structure of these compounds, was studied. An equation for predicting the toxicity of phenols is developed, toxicity increases with an increase in molecular size and with adjacent ring substi...

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Veröffentlicht in:	Bull. Environ. Contam. Toxicol.; (United States) 1984-03, Vol.32 (3), p.354-362
Hauptverfasser:	HALL, L. H, KIER, L. B
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMALS AQUATIC ORGANISMS AROMATICS Biological and medical sciences DOSES Environmental pollutants toxicology FISHES Fishes - physiology HYDROXY COMPOUNDS LETHAL DOSES Medical sciences MOLECULAR STRUCTURE ORGANIC COMPOUNDS PHENOLS Phenols - toxicity RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT Regression Analysis Structure-Activity Relationship TOXICITY Toxicology VERTEBRATES 560305 > Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987) Water
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Beschreibung
Zusammenfassung:	The relation between the acute toxicity of phenolic compounds to fish (Pimephales promelas) and the chemical structure of these compounds, was studied. An equation for predicting the toxicity of phenols is developed, toxicity increases with an increase in molecular size and with adjacent ring substitution.
ISSN:	0007-4861 1432-0800
DOI:	10.1007/BF01607509