Radiotherapy after testicular-sparing surgery for bilateral or monorchide testicular tumours: an innovative approach

Testicular-sparing surgery may avoid definitive testosterone supplementation and preserve fertility in selected cases of men presenting with bilateral testicular tumours or in case of monorchidia. Testicular-sparing surgery may enable the conservation of both endocrine function and spermatogenesis i...

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Veröffentlicht in:	Cancer radiothérapie 2013-07, Vol.17 (4), p.317-322
Hauptverfasser:	Sargos, P, Ferretti, L, Henriques de Figueiredo, B, Cornelis, F, Belhomme, S, Dallaudière, B, Richaud, P
Format:	Artikel
Sprache:	fre
Schlagworte:	Carcinoma in Situ - drug therapy Carcinoma in Situ - radiotherapy Chemotherapy, Adjuvant Clinical Trials as Topic - statistics & numerical data Combined Modality Therapy Hormone Replacement Therapy - psychology Humans Infertility, Male - prevention & control Infertility, Male - psychology Male Multicenter Studies as Topic - statistics & numerical data Neoplasms, Germ Cell and Embryonal - drug therapy Neoplasms, Germ Cell and Embryonal - psychology Neoplasms, Germ Cell and Embryonal - radiotherapy Neoplasms, Germ Cell and Embryonal - surgery Neoplasms, Multiple Primary - drug therapy Neoplasms, Multiple Primary - psychology Neoplasms, Multiple Primary - radiotherapy Neoplasms, Multiple Primary - surgery Orchiectomy - adverse effects Orchiectomy - methods Orchiectomy - psychology Organ Sparing Treatments Radiotherapy Dosage Radiotherapy, Adjuvant - methods Radiotherapy, High-Energy - adverse effects Radiotherapy, High-Energy - methods Randomized Controlled Trials as Topic - statistics & numerical data Stress, Psychological - etiology Stress, Psychological - prevention & control Testicular Neoplasms - drug therapy Testicular Neoplasms - psychology Testicular Neoplasms - radiotherapy Testicular Neoplasms - surgery Testis - pathology Testis - radiation effects Testis - surgery Testosterone - therapeutic use Treatment Outcome
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Beschreibung
Zusammenfassung:	Testicular-sparing surgery may avoid definitive testosterone supplementation and preserve fertility in selected cases of men presenting with bilateral testicular tumours or in case of monorchidia. Testicular-sparing surgery may enable the conservation of both endocrine function and spermatogenesis in selected young men in order to preserve natural fatherhood, avoid definitive androgen replacement therapy and probably improve quality of life by reducing psychosexual consequences of anorchia. The tumorectomy must be followed by an external irradiation of the remaining testicle to eradicate testicular intratubular neoplasia revealed in 82% of cases after per-surgery biopsy. This approach concerns some rare indications. Dose level and technical consideration are still debated.
ISSN:	1769-6658
DOI:	10.1016/j.canrad.2013.03.005