Neurotoxicity of styrene in production and polymerization workers
Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower...
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| Veröffentlicht in: | Environmental research 1978-02, Vol.15 (1), p.133-138 |
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| creator | Lilis, Ruth Lorimer, William V. Diamond, Sidney Selikoff, Irving J. |
| description | Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower extremities was observed in 8.5% of the cases. Radial nerve conduction velocity (RNCV) was found to be less than 55 m/second in 18.8% tested cases. Peroneal nerve conduction velocity (PNCV) was less than 40 m/second in 16.4% of the tested workers. A consistent decrement of PNCV with duration of styrene exposure was found: no such trend was detected for RNCV. |
| doi_str_mv | 10.1016/0013-9351(78)90086-5 |
| format | Article |
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Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower extremities was observed in 8.5% of the cases. Radial nerve conduction velocity (RNCV) was found to be less than 55 m/second in 18.8% tested cases. Peroneal nerve conduction velocity (PNCV) was less than 40 m/second in 16.4% of the tested workers. A consistent decrement of PNCV with duration of styrene exposure was found: no such trend was detected for RNCV.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1016/0013-9351(78)90086-5</identifier><identifier>PMID: 202448</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Air Pollutants - toxicity ; Air Pollutants, Occupational - toxicity ; Environmental Exposure ; Humans ; Neural Conduction - drug effects ; Occupational Diseases - chemically induced ; Peripheral Nervous System Diseases - chemically induced ; Peroneal Nerve - drug effects ; Styrenes - toxicity</subject><ispartof>Environmental research, 1978-02, Vol.15 (1), p.133-138</ispartof><rights>1978</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c453t-66a76ae55a423a04ad7f7589bc6bd4599814054b1856b841e5f308698a8c3613</citedby><cites>FETCH-LOGICAL-c453t-66a76ae55a423a04ad7f7589bc6bd4599814054b1856b841e5f308698a8c3613</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0013-9351(78)90086-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/202448$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lilis, Ruth</creatorcontrib><creatorcontrib>Lorimer, William V.</creatorcontrib><creatorcontrib>Diamond, Sidney</creatorcontrib><creatorcontrib>Selikoff, Irving J.</creatorcontrib><title>Neurotoxicity of styrene in production and polymerization workers</title><title>Environmental research</title><addtitle>Environ Res</addtitle><description>Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower extremities was observed in 8.5% of the cases. Radial nerve conduction velocity (RNCV) was found to be less than 55 m/second in 18.8% tested cases. Peroneal nerve conduction velocity (PNCV) was less than 40 m/second in 16.4% of the tested workers. A consistent decrement of PNCV with duration of styrene exposure was found: no such trend was detected for RNCV.</description><subject>Air Pollutants - toxicity</subject><subject>Air Pollutants, Occupational - toxicity</subject><subject>Environmental Exposure</subject><subject>Humans</subject><subject>Neural Conduction - drug effects</subject><subject>Occupational Diseases - chemically induced</subject><subject>Peripheral Nervous System Diseases - chemically induced</subject><subject>Peroneal Nerve - drug effects</subject><subject>Styrenes - toxicity</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS3EqxT-oIusECwCdv2IvUGqKl5SBZvuLceZSIYkLnYChK8nbSqWrEYz987VzEFoRvANwUTcYkxoqignV5m8VhhLkfIDNCFYiRQrTg_R5M9yis5ifBtawik-QcdzPGdMTtDiBbrgW__trGv7xJdJbPsADSSuSTbBF51tnW8S0xTJxld9DcH9mN3oy4d3CPEcHZWminCxr1O0frhfL5_S1evj83KxSi3jtE2FMJkwwLlhc2owM0VWZlyq3Iq8YFwpSRjmLCeSi1wyArykw0dKGmmpIHSKLsfY4aiPDmKraxctVJVpwHdRE0YwVlk2GNlotMHHGKDUm-BqE3pNsN5y01soegtFZ1LvuGk-rM32-V1eQ_G3NIIa5LtRhuHFTwdBR-ugsVC4ALbVhXf_5_8CjIp75A</recordid><startdate>197802</startdate><enddate>197802</enddate><creator>Lilis, Ruth</creator><creator>Lorimer, William V.</creator><creator>Diamond, Sidney</creator><creator>Selikoff, Irving J.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope></search><sort><creationdate>197802</creationdate><title>Neurotoxicity of styrene in production and polymerization workers</title><author>Lilis, Ruth ; Lorimer, William V. ; Diamond, Sidney ; Selikoff, Irving J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c453t-66a76ae55a423a04ad7f7589bc6bd4599814054b1856b841e5f308698a8c3613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Air Pollutants - toxicity</topic><topic>Air Pollutants, Occupational - toxicity</topic><topic>Environmental Exposure</topic><topic>Humans</topic><topic>Neural Conduction - drug effects</topic><topic>Occupational Diseases - chemically induced</topic><topic>Peripheral Nervous System Diseases - chemically induced</topic><topic>Peroneal Nerve - drug effects</topic><topic>Styrenes - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lilis, Ruth</creatorcontrib><creatorcontrib>Lorimer, William V.</creatorcontrib><creatorcontrib>Diamond, Sidney</creatorcontrib><creatorcontrib>Selikoff, Irving J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><jtitle>Environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lilis, Ruth</au><au>Lorimer, William V.</au><au>Diamond, Sidney</au><au>Selikoff, Irving J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurotoxicity of styrene in production and polymerization workers</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>1978-02</date><risdate>1978</risdate><volume>15</volume><issue>1</issue><spage>133</spage><epage>138</epage><pages>133-138</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><abstract>Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower extremities was observed in 8.5% of the cases. Radial nerve conduction velocity (RNCV) was found to be less than 55 m/second in 18.8% tested cases. Peroneal nerve conduction velocity (PNCV) was less than 40 m/second in 16.4% of the tested workers. A consistent decrement of PNCV with duration of styrene exposure was found: no such trend was detected for RNCV.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>202448</pmid><doi>10.1016/0013-9351(78)90086-5</doi><tpages>6</tpages></addata></record> |
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| ispartof | Environmental research, 1978-02, Vol.15 (1), p.133-138 |
| issn | 0013-9351 1096-0953 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Air Pollutants - toxicity Air Pollutants, Occupational - toxicity Environmental Exposure Humans Neural Conduction - drug effects Occupational Diseases - chemically induced Peripheral Nervous System Diseases - chemically induced Peroneal Nerve - drug effects Styrenes - toxicity |
| title | Neurotoxicity of styrene in production and polymerization workers |
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