Neurotoxicity of styrene in production and polymerization workers

Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower...

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Veröffentlicht in:Environmental research 1978-02, Vol.15 (1), p.133-138
Hauptverfasser: Lilis, Ruth, Lorimer, William V., Diamond, Sidney, Selikoff, Irving J.
Format: Artikel
Sprache:eng
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Zusammenfassung:Four-hundred ninety four workers exposed to styrene in a monomer manufacturing and polymerization plant were examined. Prenarcotic symptoms had been experienced by 13% of all examined workers and were significantly more frequent in those with higher styrene exposure. Distal hypoesthesia of the lower extremities was observed in 8.5% of the cases. Radial nerve conduction velocity (RNCV) was found to be less than 55 m/second in 18.8% tested cases. Peroneal nerve conduction velocity (PNCV) was less than 40 m/second in 16.4% of the tested workers. A consistent decrement of PNCV with duration of styrene exposure was found: no such trend was detected for RNCV.
ISSN:0013-9351
1096-0953
DOI:10.1016/0013-9351(78)90086-5