Localization of tyrosine-hydroxylase immunoreactive cells in rabbit retinal cultures

Tyrosine-hydroxylase immunoreactivity is demonstrable by the indirect immunofluorescence technique in a small sub-population of retinal neurones cultured from 2-day-old rabbits. Staining was only weak, restricted to a few neurones, and could not be observed in cultures of less than 10 days. Autoradi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1984-01, Vol.50 (1), p.117-120
Hauptverfasser:	Osborne, N.N., Beaton, D.W., Vigny, A., Neuhoff, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Biological and medical sciences Cell cultures. Hybridization. Fusion cells Cells, Cultured cultures Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Molecular and cellular biology rabbit Rabbits retina Retina - enzymology Tyrosine 3-Monooxygenase - metabolism tyrosine-hydroxylase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Tyrosine-hydroxylase immunoreactivity is demonstrable by the indirect immunofluorescence technique in a small sub-population of retinal neurones cultured from 2-day-old rabbits. Staining was only weak, restricted to a few neurones, and could not be observed in cultures of less than 10 days. Autoradiographical analysis of [ 3H]dopamine uptake by retinal cultures strongly suggests that neurones containing tyrosine-hydroxylase immunoreactivity have the capacity to take up exogenous dopamine. These findings are in concordance with studies on rabbit retinal preparations.
ISSN:	0304-3940 1872-7972
DOI:	10.1016/0304-3940(84)90472-5