Tumor-Initiating Ability of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) and Arochlor 1254 in the Two-Stage System of Mouse Skin Carcinogenesis

Tumor-Initiating Ability of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (TCDD) and Arochlor 1254 in the Two-Stage System of Mouse Skin Carcinogenesis

The tumor-initiating ability of TCDD was tested on mice. Although TCDD, when administered alone at a dose of 2 G per mouse, showed only a weak ability to induce cancer after 32 weeks, the chemical's ability to produce tumors was enhanced slightly when administered in conjunction with 7,12-dimet...

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Veröffentlicht in:Bulletin of environmental contamination and toxicology 1977-11, Vol.18 (5), p.522-522
Hauptverfasser: Digiovanni, John, Viaje, Aurora, Berry, David L, Slaga, Thomas J, Juchau, Mont R
Format: Artikel
Sprache:eng
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Zusammenfassung:The tumor-initiating ability of TCDD was tested on mice. Although TCDD, when administered alone at a dose of 2 G per mouse, showed only a weak ability to induce cancer after 32 weeks, the chemical's ability to produce tumors was enhanced slightly when administered in conjunction with 7,12-dimethylben
ISSN:0007-4861