Comparison of a new high-resolution monolithic column with core-shell and fully porous columns for the analysis of retinol and α-tocopherol in human serum and breast milk by ultra-high-performance liquid chromatography

The reduction of analysis time, cost, and improvement of separation efficiency are the main requirements in the development of high‐throughput assay methods in bioanalysis. It can be achieved either by ultra‐high‐performance liquid chromatography (UHPLC) using stationary phases with small particles...

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Veröffentlicht in:	Journal of separation science 2013-07, Vol.36 (14), p.2223-2230
Hauptverfasser:	Kučerová, Barbora, Krčmová, Lenka, Solichová, Dagmar, Plíšek, Jiří, Solich, Petr
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Tocopherol - analysis alpha-Tocopherol - blood Bioanalysis Biological and medical sciences Chromatography, High Pressure Liquid - instrumentation Chromatography, High Pressure Liquid - methods Core-shell Delivery. Postpartum. Lactation Female Gynecology. Andrology. Obstetrics High-resolution monolith Humans Investigative techniques, diagnostic techniques (general aspects) Liposoluble vitamins Maternal, fetal and perinatal monitoring Medical sciences Milk, Human - chemistry Miscellaneous. Technology Particle Size Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Porosity Resins, Synthetic - chemistry Vitamin A - analysis Vitamin A - blood
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Zusammenfassung:	The reduction of analysis time, cost, and improvement of separation efficiency are the main requirements in the development of high‐throughput assay methods in bioanalysis. It can be achieved either by ultra‐high‐performance liquid chromatography (UHPLC) using stationary phases with small particles (
ISSN:	1615-9306 1615-9314
DOI:	10.1002/jssc.201300242