Topographical distribution of dimethylbenz(a)anthracene-induced rat mammary tumors

Intravenous administration of dimethylbenz(a)anthracene (DMBA) in the rat induces multiple mammary tumors. The nodules, benign or malignant, develop preferentially in the thoracic part of the milk line. Actinomycin D interferes with the carcinogenic action of DMBA, but it does not alter the regional...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of clinical and laboratory science 1983-01, Vol.13 (4), p.289-290
1. Verfasser:	Kellen, J A
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Animals Benz(a)Anthracenes Female Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - pathology Rats Rats, Inbred Strains
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Intravenous administration of dimethylbenz(a)anthracene (DMBA) in the rat induces multiple mammary tumors. The nodules, benign or malignant, develop preferentially in the thoracic part of the milk line. Actinomycin D interferes with the carcinogenic action of DMBA, but it does not alter the regional distribution of the tumors formed. Evaluation of experimental data, using this tumor model, should take tumor topography into consideration.
ISSN:	0091-7370