The role of complement in trauma and fracture healing
Highlights • We outline less known roles of complement after trauma and during fracture healing. • Complement intensively crosstalks with the coagulation, apoptosis and TLR system. • Complement affects tissue regeneration after fracture and bone turnover. • Osteoblasts and osteoclast are involved in...
Gespeichert in:
| Veröffentlicht in: | Seminars in immunology 2013-02, Vol.25 (1), p.73-78 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 78 |
|---|---|
| container_issue | 1 |
| container_start_page | 73 |
| container_title | Seminars in immunology |
| container_volume | 25 |
| creator | Huber-Lang, Markus Kovtun, Anna Ignatius, Anita |
| description | Highlights • We outline less known roles of complement after trauma and during fracture healing. • Complement intensively crosstalks with the coagulation, apoptosis and TLR system. • Complement affects tissue regeneration after fracture and bone turnover. • Osteoblasts and osteoclast are involved in local complement activation and response. |
| doi_str_mv | 10.1016/j.smim.2013.05.006 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1399056346</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1044532313000353</els_id><sourcerecordid>1399056346</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-a821cb11a0d3719243a964aa5745db686bacf1410c2d379bd288328e3554b3793</originalsourceid><addsrcrecordid>eNp9kctKxTAURYMovn_AgXTopDUnr5uCCCK-QHCgjkOanmqufVyTVvDvTbnqwIGjhLD2hqxNyBHQAiio02URO98VjAIvqCwoVRtkF2ipcq5Ab853IXLJGd8hezEuKaVcaNgmO4wvlNal3iXy6RWzMLSYDU3mhm7VYof9mPk-G4OdOpvZvs6aYN04Bcxe0ba-fzkgW41tIx5-n_vk-frq6fI2v3-4ubu8uM-dkHLMrWbgKgBLa76AkgluSyWslQsh60ppVVnXgADqWALKqmZac6aRSymq9MD3ycm6dxWG9wnjaDofHbat7XGYogFellQqLlRC2Rp1YYgxYGNWwXc2fBqgZtZllmbWZWZdhkqTdKXQ8Xf_VHVY_0Z-_CTgbA1g-uWHx2Ci89g7rH1AN5p68P_3n_-Ju6TPO9u-4SfG5TCFPvkzYCIz1DzOg817AZ-3kpx_AWFJjkM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1399056346</pqid></control><display><type>article</type><title>The role of complement in trauma and fracture healing</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Huber-Lang, Markus ; Kovtun, Anna ; Ignatius, Anita</creator><creatorcontrib>Huber-Lang, Markus ; Kovtun, Anna ; Ignatius, Anita</creatorcontrib><description>Highlights • We outline less known roles of complement after trauma and during fracture healing. • Complement intensively crosstalks with the coagulation, apoptosis and TLR system. • Complement affects tissue regeneration after fracture and bone turnover. • Osteoblasts and osteoclast are involved in local complement activation and response.</description><identifier>ISSN: 1044-5323</identifier><identifier>EISSN: 1096-3618</identifier><identifier>DOI: 10.1016/j.smim.2013.05.006</identifier><identifier>PMID: 23768898</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Allergy and Immunology ; Animals ; Apoptosis ; Blood Coagulation ; Bone ; Complement ; Complement System Proteins - physiology ; Fracture ; Fracture Healing - immunology ; Humans ; Immunity, Innate ; Osteogenesis - immunology ; Receptors, Pattern Recognition - immunology ; Regeneration ; Trauma ; Wounds and Injuries - immunology</subject><ispartof>Seminars in immunology, 2013-02, Vol.25 (1), p.73-78</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-a821cb11a0d3719243a964aa5745db686bacf1410c2d379bd288328e3554b3793</citedby><cites>FETCH-LOGICAL-c455t-a821cb11a0d3719243a964aa5745db686bacf1410c2d379bd288328e3554b3793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.smim.2013.05.006$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23768898$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huber-Lang, Markus</creatorcontrib><creatorcontrib>Kovtun, Anna</creatorcontrib><creatorcontrib>Ignatius, Anita</creatorcontrib><title>The role of complement in trauma and fracture healing</title><title>Seminars in immunology</title><addtitle>Semin Immunol</addtitle><description>Highlights • We outline less known roles of complement after trauma and during fracture healing. • Complement intensively crosstalks with the coagulation, apoptosis and TLR system. • Complement affects tissue regeneration after fracture and bone turnover. • Osteoblasts and osteoclast are involved in local complement activation and response.</description><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Apoptosis</subject><subject>Blood Coagulation</subject><subject>Bone</subject><subject>Complement</subject><subject>Complement System Proteins - physiology</subject><subject>Fracture</subject><subject>Fracture Healing - immunology</subject><subject>Humans</subject><subject>Immunity, Innate</subject><subject>Osteogenesis - immunology</subject><subject>Receptors, Pattern Recognition - immunology</subject><subject>Regeneration</subject><subject>Trauma</subject><subject>Wounds and Injuries - immunology</subject><issn>1044-5323</issn><issn>1096-3618</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kctKxTAURYMovn_AgXTopDUnr5uCCCK-QHCgjkOanmqufVyTVvDvTbnqwIGjhLD2hqxNyBHQAiio02URO98VjAIvqCwoVRtkF2ipcq5Ab853IXLJGd8hezEuKaVcaNgmO4wvlNal3iXy6RWzMLSYDU3mhm7VYof9mPk-G4OdOpvZvs6aYN04Bcxe0ba-fzkgW41tIx5-n_vk-frq6fI2v3-4ubu8uM-dkHLMrWbgKgBLa76AkgluSyWslQsh60ppVVnXgADqWALKqmZac6aRSymq9MD3ycm6dxWG9wnjaDofHbat7XGYogFellQqLlRC2Rp1YYgxYGNWwXc2fBqgZtZllmbWZWZdhkqTdKXQ8Xf_VHVY_0Z-_CTgbA1g-uWHx2Ci89g7rH1AN5p68P_3n_-Ju6TPO9u-4SfG5TCFPvkzYCIz1DzOg817AZ-3kpx_AWFJjkM</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Huber-Lang, Markus</creator><creator>Kovtun, Anna</creator><creator>Ignatius, Anita</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130201</creationdate><title>The role of complement in trauma and fracture healing</title><author>Huber-Lang, Markus ; Kovtun, Anna ; Ignatius, Anita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-a821cb11a0d3719243a964aa5745db686bacf1410c2d379bd288328e3554b3793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Apoptosis</topic><topic>Blood Coagulation</topic><topic>Bone</topic><topic>Complement</topic><topic>Complement System Proteins - physiology</topic><topic>Fracture</topic><topic>Fracture Healing - immunology</topic><topic>Humans</topic><topic>Immunity, Innate</topic><topic>Osteogenesis - immunology</topic><topic>Receptors, Pattern Recognition - immunology</topic><topic>Regeneration</topic><topic>Trauma</topic><topic>Wounds and Injuries - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huber-Lang, Markus</creatorcontrib><creatorcontrib>Kovtun, Anna</creatorcontrib><creatorcontrib>Ignatius, Anita</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huber-Lang, Markus</au><au>Kovtun, Anna</au><au>Ignatius, Anita</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of complement in trauma and fracture healing</atitle><jtitle>Seminars in immunology</jtitle><addtitle>Semin Immunol</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>25</volume><issue>1</issue><spage>73</spage><epage>78</epage><pages>73-78</pages><issn>1044-5323</issn><eissn>1096-3618</eissn><abstract>Highlights • We outline less known roles of complement after trauma and during fracture healing. • Complement intensively crosstalks with the coagulation, apoptosis and TLR system. • Complement affects tissue regeneration after fracture and bone turnover. • Osteoblasts and osteoclast are involved in local complement activation and response.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>23768898</pmid><doi>10.1016/j.smim.2013.05.006</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1044-5323 |
| ispartof | Seminars in immunology, 2013-02, Vol.25 (1), p.73-78 |
| issn | 1044-5323 1096-3618 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1399056346 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Allergy and Immunology Animals Apoptosis Blood Coagulation Bone Complement Complement System Proteins - physiology Fracture Fracture Healing - immunology Humans Immunity, Innate Osteogenesis - immunology Receptors, Pattern Recognition - immunology Regeneration Trauma Wounds and Injuries - immunology |
| title | The role of complement in trauma and fracture healing |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T10%3A20%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20role%20of%20complement%20in%20trauma%20and%20fracture%20healing&rft.jtitle=Seminars%20in%20immunology&rft.au=Huber-Lang,%20Markus&rft.date=2013-02-01&rft.volume=25&rft.issue=1&rft.spage=73&rft.epage=78&rft.pages=73-78&rft.issn=1044-5323&rft.eissn=1096-3618&rft_id=info:doi/10.1016/j.smim.2013.05.006&rft_dat=%3Cproquest_cross%3E1399056346%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1399056346&rft_id=info:pmid/23768898&rft_els_id=S1044532313000353&rfr_iscdi=true |