T cell-dependent B cell activation
One paper, among many, on T-cell dependent B-cell activation, states the authors, is correct and has successfully withstood 9 years of work in many laboratories. Schimpl and Wecker (1975) clearly distinguish, already then, 3 phases in B cell responses: induction, proliferation and maturation, which...
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Veröffentlicht in: | Immunological reviews 1984 (78), p.211-224 |
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container_title | Immunological reviews |
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creator | COUTINHO, A POBOR, G PETTERSSON, S LEANDERSSON, T FORSGREN, S PEREIRA, P BANDEIRA, A MARTINEZ, A. C |
description | One paper, among many, on T-cell dependent B-cell activation, states the authors, is correct and has successfully withstood 9 years of work in many laboratories. Schimpl and Wecker (1975) clearly distinguish, already then, 3 phases in B cell responses: induction, proliferation and maturation, which are separately controlled. Moreover, they point out that only the inductive phase is selective as to clonal specificities, while growth and maturation are controlled by polyclonal (non-specific) ligands and cellular structures "other than specific Ig receptors". |
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C</creatorcontrib><title>T cell-dependent B cell activation</title><title>Immunological reviews</title><description>One paper, among many, on T-cell dependent B-cell activation, states the authors, is correct and has successfully withstood 9 years of work in many laboratories. Schimpl and Wecker (1975) clearly distinguish, already then, 3 phases in B cell responses: induction, proliferation and maturation, which are separately controlled. Moreover, they point out that only the inductive phase is selective as to clonal specificities, while growth and maturation are controlled by polyclonal (non-specific) ligands and cellular structures "other than specific Ig receptors".</description><subject>Analysis of the immune response. Humoral and cellular immunity</subject><subject>Biological and medical sciences</subject><subject>Cell interactions</subject><subject>Fundamental and applied biological sciences. 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Psychology</topic><topic>Fundamental immunology</topic><topic>Immunobiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>COUTINHO, A</creatorcontrib><creatorcontrib>POBOR, G</creatorcontrib><creatorcontrib>PETTERSSON, S</creatorcontrib><creatorcontrib>LEANDERSSON, T</creatorcontrib><creatorcontrib>FORSGREN, S</creatorcontrib><creatorcontrib>PEREIRA, P</creatorcontrib><creatorcontrib>BANDEIRA, A</creatorcontrib><creatorcontrib>MARTINEZ, A. C</creatorcontrib><collection>Pascal-Francis</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Immunological reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>COUTINHO, A</au><au>POBOR, G</au><au>PETTERSSON, S</au><au>LEANDERSSON, T</au><au>FORSGREN, S</au><au>PEREIRA, P</au><au>BANDEIRA, A</au><au>MARTINEZ, A. 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source | Wiley Online Library Journals Frontfile Complete |
subjects | Analysis of the immune response. Humoral and cellular immunity Biological and medical sciences Cell interactions Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology |
title | T cell-dependent B cell activation |
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