Use of structure-reactivity relationships to estimate hydrolytic persistence of carbamate pesticides

Linear free energy relationships are given for use in estimating alkaline hydrolysis of carbamate pesticides in water as applied to environmental conditions. Plots of the second-order alkaline hydrolysis rate constants versus p K a of the resulting alcohol are given for N, N-dimethyl-, N-methyl- N-phenyl-, N-methyl-, and N-phenyl-carbamates. Use of these relationships allows one to estimate rate constants for specific compounds and make general statements about hydrolytic stability of classes of compounds.