Evidence for the protective effect of metallothioneins against inorganic mercury injuries to fish

Following previous observations indicative of a protective action against mercury exposure due to metal-containing protein (metallothioneins) in eels (Anguilla anguilla), the toxicity of a lethal dose of mercury (10 ppm) to sea water adapted animals with or without metallothioneins in the gill tissu...

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Veröffentlicht in:Bull. Environ. Contam. Toxicol.; (United States) 1979-09, Vol.23 (1-2), p.218-219
1. Verfasser: Bouquegneau, J M
Format: Artikel
Sprache:eng
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Zusammenfassung:Following previous observations indicative of a protective action against mercury exposure due to metal-containing protein (metallothioneins) in eels (Anguilla anguilla), the toxicity of a lethal dose of mercury (10 ppm) to sea water adapted animals with or without metallothioneins in the gill tissues was examined. The presence of metallothioneins was induced by petreatment with a sub-lethal dose of mercury in the form of exposure to sea water containing 0.1 ppm Hg as mecuric chloride. A similar pretreatment involving exposure to 15 ppm Cd as cadmium chloride was also tested. The mortality of the pretreated specimens was markedly below that of the controls, the protective effect of cadmium exposure at the 15 ppm level being slightly superior to that of mercury at the 0.1 ppm level.
ISSN:0007-4861
1432-0800
DOI:10.1007/BF01769945