Salivary gland dysfunction following radioactive iodine therapy

Radioactive iodine is used extensively for the treatment of thyrotoxicosis and thyroid carcinoma. Iodine is actively taken up by the salivary glands and, following its use, salivary dysfunction may result as a consequence of radiation damage. The literature is reviewed and a case is reported in whic...

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Veröffentlicht in:	Oral Surg., Oral Med., Oral Pathol.; (United States) Oral Med., Oral Pathol.; (United States), 1983-02, Vol.55 (2), p.138-141
Hauptverfasser:	Wiesenfeld, D., Webster, G., Cameron, F., Ferguson, M.M., MacFadyen, E.E., MacFarlane, T.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-) 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man Adult BODY CARCINOMAS CARIES Dental Caries - etiology DISEASES ENDOCRINE DISEASES ENDOCRINE GLANDS Female GLANDS Humans HYPERTHYROIDISM Iodine Radioisotopes - adverse effects Iodine Radioisotopes - therapeutic use MEDICINE NEOPLASMS NUCLEAR MEDICINE ORGANS PATHOLOGICAL CHANGES RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY SALIVARY GLANDS Salivary Glands - physiopathology Salivary Glands - radiation effects SIDE EFFECTS THERAPY THYROID Thyroid Neoplasms - drug therapy Xerostomia - etiology Xerostomia - physiopathology
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Beschreibung
Zusammenfassung:	Radioactive iodine is used extensively for the treatment of thyrotoxicosis and thyroid carcinoma. Iodine is actively taken up by the salivary glands and, following its use, salivary dysfunction may result as a consequence of radiation damage. The literature is reviewed and a case is reported in which a patient presented with a significant increase in caries rate attributed to salivary dysfunction following radioactive iodine therapy for a thyroid carcinoma.
ISSN:	0030-4220 1878-2175
DOI:	10.1016/0030-4220(83)90168-8