Effects of copper, zinc and paraquat on acetylcholinesterase activity in carp ( Cyprinus carpio L.)

The effects of pH and substrate concentration on acetylcholinesterase (AChE) activity were studied in serum, brain, heart and muscle of common carp ( Cyprinus carpio L.). Effects of zinc chloride, paraquat (1,1′-dimethyl-4,4′-dipyridinium dichloride) and copper sulphate from in vivo and in vitro exp...

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Veröffentlicht in:Aquatic toxicology 1984-01, Vol.5 (1), p.23-31
Hauptverfasser: Nemcsók, J., Németh, Á., Buzás, Zs, Boross, L.
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Sprache:eng
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Zusammenfassung:The effects of pH and substrate concentration on acetylcholinesterase (AChE) activity were studied in serum, brain, heart and muscle of common carp ( Cyprinus carpio L.). Effects of zinc chloride, paraquat (1,1′-dimethyl-4,4′-dipyridinium dichloride) and copper sulphate from in vivo and in vitro exposure were studied on these AChE activities. Zinc chloride did not decrease AChE activity in any of the organs studied in vivo or in vitro. In contrast, paraquat, competitively, and copper sulphate, in a mixed way, inhibited acetylcholinesterase activity. Inhibition of AChE in fish exposed to these two pesticides may serve as an indicator of hazard due to application of these chemicals in the natural environment.
ISSN:0166-445X
1879-1514
DOI:10.1016/0166-445X(84)90029-8