Global stability of a two-stage epidemic model with generalized non-linear incidence

A multi-stage model of disease transmission, which incorporates a generalized non-linear incidence function, is developed and analysed qualitatively. The model exhibits two steady states namely: a disease-free state and a unique endemic state. A global stability of the model reveals that the disease...

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Veröffentlicht in:Mathematics and computers in simulation 2002-07, Vol.60 (1), p.107-118
Hauptverfasser: Moghadas, S.M., Gumel, A.B.
Format: Artikel
Sprache:eng
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Zusammenfassung:A multi-stage model of disease transmission, which incorporates a generalized non-linear incidence function, is developed and analysed qualitatively. The model exhibits two steady states namely: a disease-free state and a unique endemic state. A global stability of the model reveals that the disease-free equilibrium is globally asymptotically stable (and therefore the disease can be eradicated) provided a certain threshold R 0 (known as the basic reproductive number) is less than unity. On the other hand, the unique endemic equilibrium is globally asymptotically stable for R 0>1 .
ISSN:0378-4754
1872-7166
DOI:10.1016/S0378-4754(02)00002-2