Characterization of the mechanical and biological properties of a new alumina scaffold

In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. The results obtained showed that this scaffold has high...

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Veröffentlicht in:Journal of applied biomaterials & functional materials 2013-01, Vol.11 (1), p.e18-25
Hauptverfasser: Batista, Patrícia S P, Rodrigues, Miguel A A, Silva, Daniela M R, Morgado, Patrícia I C, Henriques, Joaquim P, Almeida, Maria O, Silva, Abílio P, Correia, Ilídio J
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Sprache:eng
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Zusammenfassung:In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.
ISSN:2280-8000
2280-8000
DOI:10.5301/JABFM.2012.9264