Serum coenzyme Q10 levels are associated with coronary flow reserve in hemodialysis patients

Accelerated atherosclerosis is the major cause of mortality in patients on chronic hemodialysis (HD). The aim of this study was to evaluate the relation between coenzyme Q10 (CoQ10) levels and coronary flow reserve (CFR) in HD patients as an indicator of atherosclerosis. Seventy‐one chronic HD patie...

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Veröffentlicht in:	Hemodialysis international 2013-07, Vol.17 (3), p.339-345
Hauptverfasser:	Macunluoglu, Beyza, Kaya, Yuksel, Atakan, Aydin, Ari, Elif, Kaspar, Cigdem, Demir, Halit, Alp, Hamit Hakan, Asicioglu, Ebru, Kedrah, Alla Eldeen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atherosclerosis - blood Atherosclerosis - diagnostic imaging Atherosclerosis - physiopathology Blood Flow Velocity Case-Control Studies coenzyme Q10 Coronary Circulation - physiology Coronary flow reserve Coronary Vessels - diagnostic imaging Female hemodialysis Humans Male Middle Aged Renal Dialysis Ubiquinone - analogs & derivatives Ubiquinone - blood Ultrasonography
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Zusammenfassung:	Accelerated atherosclerosis is the major cause of mortality in patients on chronic hemodialysis (HD). The aim of this study was to evaluate the relation between coenzyme Q10 (CoQ10) levels and coronary flow reserve (CFR) in HD patients as an indicator of atherosclerosis. Seventy‐one chronic HD patients and 65 age‐ and sex‐matched healthy individuals were included in the study. Plasma CoQ10 levels were performed by high‐performance liquid chromatography measurements. CFR was assessed by transthoracic Doppler echocardiography. Serum CoQ10 levels (1.36 ± 0.43 vs. 2.53 ± 0.55, P
ISSN:	1492-7535 1542-4758
DOI:	10.1111/hdi.12001