Relationship of Body Mass Index and Arm Anthropometry to Outcomes after Pediatric Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

Abstract Although nutritional status may adversely affect various health outcomes, the relationship between anthropometry and outcomes after hematopoietic cell transplantation (HCT) has not been fully studied in children. We analyzed the impact of pre-HCT body mass index (BMI), arm muscle area, and...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2013-07, Vol.19 (7), p.1081-1086
Hauptverfasser:	Hoffmeister, Paul A, Storer, Barry E, Macris, Paula Charuhas, Carpenter, Paul A, Baker, K. Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Anthropometry Antineoplastic Agents - therapeutic use Arm - anatomy & histology Arm anthropometry Body Mass Index Child Child, Preschool Children Chronic Disease Female Graft vs Host Disease - diagnosis Graft vs Host Disease - pathology Graft vs Host Disease - therapy Hematologic malignancy Hematologic Neoplasms - diagnosis Hematologic Neoplasms - pathology Hematologic Neoplasms - therapy Hematology, Oncology and Palliative Medicine Hematopoietic cell transplantation Hematopoietic Stem Cell Transplantation Humans Male Muscle, Skeletal - anatomy & histology Proportional Hazards Models Retrospective Studies Subcutaneous Fat - anatomy & histology Survival Analysis Transplantation Conditioning Transplantation, Homologous Treatment Outcome
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Zusammenfassung:	Abstract Although nutritional status may adversely affect various health outcomes, the relationship between anthropometry and outcomes after hematopoietic cell transplantation (HCT) has not been fully studied in children. We analyzed the impact of pre-HCT body mass index (BMI), arm muscle area, and arm fat area on outcomes in 733 patients age 2-18 years who underwent allogeneic HCT for a hematologic malignancy between 1985 and 2009. We evaluated these 3 variables according to patient group based on age- and sex-adjusted percentiles for BMI, arm muscle area (
ISSN:	1083-8791 1523-6536
DOI:	10.1016/j.bbmt.2013.04.017