Vitamin D: a negative acute phase reactant

Objective We evaluated the effect of the systemic inflammatory response (SIR), as provoked by elective orthopaedic surgery, on serum vitamin D [25-(OH)D]. Methods Serum 25-(OH)D, serum vitamin D binding protein (VDBP) and urinary VDBP were measured in 30 patients before and 48-hours after knee or hi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical pathology 2013-07, Vol.66 (7), p.620-622
Hauptverfasser:	Waldron, Jenna Louise, Ashby, Helen L, Cornes, Michael P, Bechervaise, Julia, Razavi, Cyrus, Thomas, Osmond L, Chugh, Sanjiv, Deshpande, Shreeram, Ford, Clare, Gama, Rousseau
Format:	Artikel
Sprache:	eng
Schlagworte:	ACUTE PHASE PROTEINS Acute-Phase Proteins - metabolism Arthroplasty, Replacement, Hip Arthroplasty, Replacement, Knee Biomarkers - metabolism Biomarkers - urine C-Reactive Protein - metabolism Humans INFLAMMATION Postoperative Complications - blood Postoperative Complications - urine VITAMIN D Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - etiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Objective We evaluated the effect of the systemic inflammatory response (SIR), as provoked by elective orthopaedic surgery, on serum vitamin D [25-(OH)D]. Methods Serum 25-(OH)D, serum vitamin D binding protein (VDBP) and urinary VDBP were measured in 30 patients before and 48-hours after knee or hip arthroplasty. C-reactive protein (CRP) was measured to assess the SIR. Results The mean (SD) CRP increased following surgery [5.0 (5.5) vs 116.0 (81.2) mg/L; P
ISSN:	0021-9746 1472-4146
DOI:	10.1136/jclinpath-2012-201301