Impact of International Normalized Ratio and Activated Clotting Time on Unfractionated Heparin Dosing During Ablation of Atrial Fibrillation

Impact of International Normalized Ratio and Activated Clotting Time on Unfractionated Heparin Dosing During Ablation of Atrial Fibrillation

BACKGROUND—For ablation of atrial fibrillation, it is unclear how baseline international normalized ratio (INR) affects the dosing of unfractionated heparin (UFH). METHODS AND RESULTS—A retrospective review of 170 consecutive patients undergoing atrial fibrillation ablation with baseline activated c...

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Veröffentlicht in:Circulation. Arrhythmia and electrophysiology 2013-06, Vol.6 (3), p.491-496
Hauptverfasser: Hamam, Ismail, Daoud, Emile G, Zhang, Jianying, Kalbfleisch, Steven J, Augostini, Ralph, Winner, Marshall, Tsai, Shane, Rhodes, Troy E, Houmsse, Mahmoud, Liu, Zhenguo, Love, Charles J, Tyler, Jaret, Sachdev, Molly, Weiss, Raul, Hummel, John D
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Atrial Fibrillation - diagnosis
Atrial Fibrillation - drug therapy
Atrial Fibrillation - surgery
Blood Coagulation - drug effects
Catheter Ablation - adverse effects
Catheter Ablation - methods
Cohort Studies
Dose-Response Relationship, Drug
Electrocardiography - methods
Female
Follow-Up Studies
Heparin - administration & dosage
Humans
International Normalized Ratio
Intraoperative Care - methods
Male
Middle Aged
Multivariate Analysis
Regression Analysis
Retrospective Studies
Risk Assessment
Time Factors
Treatment Outcome
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Beschreibung
Zusammenfassung:BACKGROUND—For ablation of atrial fibrillation, it is unclear how baseline international normalized ratio (INR) affects the dosing of unfractionated heparin (UFH). METHODS AND RESULTS—A retrospective review of 170 consecutive patients undergoing atrial fibrillation ablation with baseline activated clotting time (ACT) and INR values was performed. Patients were grouped according to INR
ISSN:1941-3149
1941-3084
DOI:10.1161/CIRCEP.113.979088