Effect of early measles vaccination (AIK-C strain) for preterm infants

Background The level of maternal antibodies decreases more quickly in preterm than term infants, leaving them unprotected against measles. To protect premature infants from measles, an early vaccination trial was investigated. Methods Changes in the serum measles neutralization test (NT) antibody ti...

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Veröffentlicht in:	Pediatrics international 2013-04, Vol.55 (2), p.163-168
Hauptverfasser:	Ichikawa, Tomonori, Tsuji, Atsutoshi, Fujino, Motoko, Kusano, Ryousuke, Sugiyama, Ryusuke, Oomori, Sayu, Mori, Kazuhiro, Maeyama, Katsuhiro, Nakayama, Tetsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Age AIK-C Antibodies, Viral - immunology Female Humans Immunization Infant Infant, Newborn Infant, Premature Infant, Premature, Diseases - epidemiology Infant, Premature, Diseases - immunology Infant, Premature, Diseases - prevention & control Japan - epidemiology Male Measles Measles - epidemiology Measles - immunology Measles - prevention & control measles vaccination Measles Vaccine - immunology Measles virus - immunology neutralization test antibody Pediatrics preterm infants Retrospective Studies Time Factors Vaccination - methods Vaccines
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Zusammenfassung:	Background The level of maternal antibodies decreases more quickly in preterm than term infants, leaving them unprotected against measles. To protect premature infants from measles, an early vaccination trial was investigated. Methods Changes in the serum measles neutralization test (NT) antibody titer were examined in 152 infants (average gestational period, 29 weeks; average birthweight, 1203 g). Results The average antibody titer (2n) was 23.5 at birth and 22.2 at 1–3 months of age, and in all cases, NT antibody titer decreased to
ISSN:	1328-8067 1442-200X
DOI:	10.1111/ped.12064