Quantitative Genetics: Heritability Is Not Always Missing
Quantitative trait loci (QTLs) underlying multifactorial disorders explain little of the heritability — most is ‘missing’. A new yeast study has identified QTLs which explain most heritability in traits. Why is heritability missing in human diseases but not here?
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| Veröffentlicht in: | Current biology 2013-04, Vol.23 (7), p.R276-R278 |
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| container_end_page | R278 |
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| container_title | Current biology |
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| creator | Brookfield, John F.Y. |
| description | Quantitative trait loci (QTLs) underlying multifactorial disorders explain little of the heritability — most is ‘missing’. A new yeast study has identified QTLs which explain most heritability in traits. Why is heritability missing in human diseases but not here? |
| doi_str_mv | 10.1016/j.cub.2013.02.040 |
| format | Article |
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| ispartof | Current biology, 2013-04, Vol.23 (7), p.R276-R278 |
| issn | 0960-9822 1879-0445 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Cell Press Free Archives; EZB-FREE-00999 freely available EZB journals |
| subjects | Genetic Predisposition to Disease - genetics Genome-Wide Association Study - methods Genome-Wide Association Study - trends heritability human diseases Humans Inheritance Patterns - genetics Models, Genetic quantitative trait loci Quantitative Trait Loci - genetics Yeasts |
| title | Quantitative Genetics: Heritability Is Not Always Missing |
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