Reduced serologic response to mumps, measles, and rubella vaccination in patients treated with intravenous immunoglobulin for Kawasaki disease

[...]we compared the patients who received 1 dose of IVIG (n = 40) or 2 doses (n = 18) of IVIG, and found no differences (seroprotection proportions against measles: 55% vs 61%, P = .664; mumps: 80% vs 72%, P = .511; and rubella: 93% vs 78%, P = .111, respectively). [...]we recommend postponing the...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2013-06, Vol.131 (6), p.1701-1703
Hauptverfasser:	Tacke, Carline E., MD, Smits, Gaby P., MSc, van der Klis, Fiona R.M., PhD, Kuipers, Irene M., MD, PhD, Zaaijer, Hans L., MD, PhD, Kuijpers, Taco W., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Autism Case-Control Studies Child Child, Preschool Children & youth Humans Immunization Immunoglobulins, Intravenous Infant Measles-Mumps-Rubella Vaccine - immunology Mucocutaneous Lymph Node Syndrome - immunology Mucocutaneous Lymph Node Syndrome - therapy Mumps Vaccination Vaccines
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Zusammenfassung:	[...]we compared the patients who received 1 dose of IVIG (n = 40) or 2 doses (n = 18) of IVIG, and found no differences (seroprotection proportions against measles: 55% vs 61%, P = .664; mumps: 80% vs 72%, P = .511; and rubella: 93% vs 78%, P = .111, respectively). [...]we recommend postponing the MMR vaccination to at least 9 months after IVIG administration and aim at an increased awareness of the guidelines.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2013.01.045